*bowed legs
*decrease muscle tone
*prominent forehead
*spinal stenosis
*short stature

One in 25.000
Rare
Disease can evolve anywhere

Infants who receive the abnormal gene from both parents don't often live beyond a few month

1.The availability of somatotropin (recombinant human growth hormone) has revolutionized the treatment of short stature.

2.Wide, multilevel laminectomies extending to the pedicles and lateral recesses with foraminotomies may be necessary. Extradural removal of herniated disc material is performed as necessary.

3.Surgical correction of genu varum may be required. It may be in the form of proximal tibiofibular osteotomy or proximal and distal fibular epiphysiodesis.