Clinical Description

Symptoms:
1) short height
2) weak muscles
3) slanted eyes
4) intellectual disability
5) heart defects
Occurrence:
One in 1,000
Common
More common in Hispanics and White
Older mothers
Prognosis: variable depending on condition of heart
80% reach age 50 and beyond
Treatment: No specific treatment
Major surgery
Obesity = exercise
Behavioral training

Clinical Description