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1. Eukaryotes have a nucleus, while Prokaryotes do not.
2. Eukaryotes have membrane-bound organelles like mitochondria, chloroplasts, and vacuoles; Prokaryotes do not.
3. All prokaryotes are unicellular, some eukaryotes are unicellular, but many are multicellular.
3 Differences between prokaryotes and eukaryotes' structures: