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Definition:Duplication results from an unequal crossing-over between misaligned homologous chromosomes during meiosis. It may involve a replication of a portion of DNA, or an entire chromosome.
Example:
Charcot-Marie-Tooth disease type I: characterized by abnormalities in myelin, the fatty substance that covers nerve cells, protecting them and helping to conduct nerve impulses. These abnormalities slow the transmission of nerve impulses.
Duplication