Respiratory system complications

Bronchiectasis. Cystic fibrosis is one of the leading causes of bronchiectasis, a condition in which damaged airways widen and become flabby and scarred.
Chronic infections. Thick mucus in the lungs and sinuses provide an excellent breeding ground for bacteria. Most people with cystic fibrosis have almost constant infections in their lungs and sinuses.
Collapsed lung. Repeated lung infections damage the lungs, making it more likely for the lung to collapse.
Nasal polyps. Because the lining inside the nose is inflamed and swollen, it's more likely to develop large or multiple polyps — soft, fleshy growths inside your nose.
Respiratory failure. Over time, cystic fibrosis can damage lung tissue so badly that it won't work anymore. Lung function typically worsens gradually, and it eventually can become life-threatening.