Management of coronary perforation

One is the initial steps is to reverse the anticoagulation. This includes the administration of protamine to reverse heparin. Protamine will also partially reverse the antithrombotic effect of enoxaparin if this antithrombin was used. Administration of platelets can be considered if abciximab has been administered. If it is greater than four hours after a maintenance dose of prasugrel or greater than six hours after a loading dose of prasugrel, then a platelet infusion should also be considered.

REVERSE ANTICOAGULANTS