-are pregnant

-are members of an at-risk subpopulation (i.e., persons in correctional facilities and MSM)

-describe sexual behaviors that put them at risk for STDs (i.e., having unprotected vaginal, anal, or oral sexual contact; having multiple sexual partners; using drugs and alcohol, and engaging in commercial or coerced sex)

-have partner(s) who have tested positive for syphilis

-are sexually active and live in areas with high syphilis morbidity

Get tested if you:

Source: http://www.cdc.gov/std/syphilis/stdfact-syphilis-detailed.html