Serotonin

Serotonin is a nuerotransmitter that regulated mood, sleep, pain, appetite, ect. MDMA releases an excess amount of serotonin which explains the elevation of mood and lack of appetite.

As the dosage of MDMA increases so does the users tolerance as well as the effects of physical and mental dependence. As the amount of serotonin needed increases the brain actually begins to deplete itself of the nuerotransmitter. This is why users usually feel the after effects of the drug for a few days after using of the drug.

Studies done on animals show that frequent exposure to MDMA damages neurons containing serotonin. Studies have shown human MDMA users experience long lasting confusion, depression, and damage to short term and perspective memory.