On Sunday, 12 October 2008, Pope Benedict XVI announced her canonisation at a ceremony at Saint Peter's Square.[10] Indians from across the world, especially people from Kerala, gathered at the ceremony in Rome. Among them was a 10-year-old Kerala boy Jinil Joseph whose clubfoot – a birth defect – was, in the judgment of Vatican officials, miraculously healed after prayers to Alphonsa in 1999.

The final ceremony for the canonisation began with the holy relics of Alphonsa being presented to the Pope by Sister Celia, Mother General of the Franciscan Clarist Congregation, the congregation to which Sister Alphonsa belonged. Sister Celia was accompanied by Vice Postulator Father Francis Vadakkel and former Kerala minister K. M. Mani, all holding lit candles. Speaking in English, the Pope declared Sister Alphonsa a saint, after reading excerpts from the Bible. The Pope himself read out the biography of Alphonsa after the ceremony.

In the homily, Pope Benedict XVI recalled Saint Alphonsa's life as one of "extreme physical and spiritual suffering."

"This exceptional woman … was convinced that her cross was the very means of reaching the heavenly banquet prepared for her by the Father", the pope stated. "By accepting the invitation to the wedding feast, and by adorning herself with the garment of God's grace through prayer and penance, she conformed her life to Christ's and now delights in the 'rich fare and choice wines' of the heavenly kingdom."

Why Was She Canonized