I picked Johnny Depp to play Dr.Manette because not only does he remind me of him "a man of very remarkable appearance in respect of the absolute whiteness of his hair, and a certain indescribable intensity of face: not an active kind, but pondering, and self communing" pg.57. He has the same personality as him. He is played a father in Sweeney Todd which gets his daughter taken away from him and he goes insane while trying to get her back.

Doctor Manette