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Disease: Venereal syphilis
An STD that was brought to Europe by sailors who were coming back from the Americas. It could damage your internal organs and could cause death.
Source:
-www.cdc.gov/std/syphilis/stdfact-syphilis.htm
-https://web.viu.ca/davies/H131/ColumbianExchange.pdf
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Inventions of the Columbian Exchange
By Erandir