His experiment was "Transforming principle" a pneumococcus bacteria. He discovered that bacteria is cab able of transforming genetic information, a process known as transformation.

For his first experiment he used bacteria to infect mice.

He used two types of bacteria, type III-S (smooth) and type II-R (rough)

Frederick Griffith was born in 1879, Hale, United Kingdom

Rough strain (non virulent) the mouse lives

Smooth strain (virulent) mouse dies

Heat killed smooth strain mouse lives

Rough strain and heat killed smooth strain mouse dies