The exploring Spanish has brought over diseases, had taken over Aztec empires, and had colonized these areas that those civilizations were occupying. The aztecs came to their end by the hands of Hernan Cortez and his men thanks to the aid of the epidemic diseases, which had also occurred when Francisco Pizarro had wiped out the Incas. The Spanish had forced some natives and slaves to work and produce sugar while also using the repartimiento system to bring in semi-voluntary native workers to mine silver.