The National Wildlife Refuge System, within the U.S. Fish and Wildlife Service, manages a national network of lands and waters set aside to conserve America’s fish, wildlife, and plants.

Astonishing biodiversity exists in Congaree National Park, the largest intact expanse of old growth bottomland hardwood forest remaining in the southeastern United States. Waters from the Congaree and Wateree Rivers sweep through the floodplain, carrying nutrients and sediments that nourish and rejuvenate this ecosystem and support the growth of national and state champion trees.

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The Okefenokee Swamp is a shallow, 438,000 acre (1,770 km²), peat-filled wetland straddling the Georgia–Florida border in the United States. A majority of the swamp is protected by the Okefenokee National Wildlife Refuge and the Okefenokee Wilderness. The Okefenokee Swamp is considered to be one of the Seven Natural Wonders of Georgia. The Okefenokee is the largest "blackwater" swamp in North America. The term Okefenokee in Native American is "land of trembling earth". The swamp was designated a National Natural Landmark in 1974.