Retinoblastoma is a mutation that happens on the 13th chromosome. It is often inherited but it is common to have it just appear. Like my case I just had it as a baby and it was not inherited.

The development of Retinoblastoma is described as a two hit model. First, a mutational event is or can be inherited. Which makes it present in the body. Then second you lose a normal allele within a particular retinal cell.

For some kids, like me, the cancer came from no where. No family history of it and it was not passed on. MYNC oncogene may be the reason for this. MYNC is protein that is needed for normal brain development and oncogene is a gene that has the potential to cause cancer. If a MYNC is over expressed or amplified it has a chance of causing a tumor.