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The benefits that are often given by clinical trial is the gaining of new treatments before they are widely available. Also you can either benefit of the new treatment or the standard treatment for your condition.
The risks being taken are that the new treatment being studied isnt better than the current standard care. The side effects or risks that a treatment has that doctors don't know about or expect. The risks of side effects are greater whit approaches with gene therapy and new biological treatments. Also health insurance and healthcare providers don't cover all patient costs for clinical trials.
Advantages vs Disadvantage