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QUESTION 8
A 25-year-old female from California presents with the acute onset on severe pain in her right wrist. She is sexually active with multiple male partners, who only intermittently use condoms.
On presentation she is febrile and examination of the right wrist revealed swelling, erythema, and pain on motion. She has a few painless papules on examination of the skin of the lower extremities.
Which of the following tests has the highest yield for establishing the epidemiologically most likely microbiologic diagnosis in this patient?
1. Blood culture
2. Synovial fluid Gram stain
3. Synovial fluid culture
4. Cervical culture
5. Oropharyngeal culture