Risk Factors

~ Rheumatoid arthritis
~ Medications such as breast cancer drugs and prostate cancer drugs,
~ Anorexia nervosa ( an eating disorder that leads to malnutrition)
~Hypoganodism
~Estrogen difeciency
~Alcohol abuse
~Cushing's disease (a tumor of the pituitary gland, responsible for secreting some of the body's hormone)
~Liver impairment
~Malabsorption syndrome such as celiac disease.