Secretion of Trypsin Inhibitor Prevents Digestion of the Pancreas Itself

It is important that the of the pancreatic juice should not become activated until they have been secreted into the intestine

Fortunately, the same cells that secrete proteolytic enzymes into the acini of the pancreas secrete simultaneously another substance called

When the pancreas becomes severely damaged or when it is blocked, large quantities of pancreatic secretion sometimes become pooled in the damaged areas of the pancreas

Under these conditions, the effect of trypsin inhibitor leads to the and of the pancreas and its pancreatic secretion, giving rise to the condition called


It is sometimes lethal because of

And, it usually leads to a lifetime of

proteolytic enzymes

Trypsin Inhibitor

Acute

pancreatic insufficiency

activation

digestion

Pancreatitis

circulatory shock