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29. Describe the process of DNA replication.

1). DNA helices unwind from the nucleosomes
2). Helicase untwists the double helix into 2 complementary nucleotide chains exposing the nitrogenous bases
3). Each nucleotide strand serves as a template for building a new complementary strand. Occurs at the replication fork
4). The replisome uses RNA primers to begin DNA synthesis of 2nd strand
5). DNA polymerase III continues from the primer and covalently adds complementary nucleotides to the template
6). DNA ligase splices the short segments together
7). After replication, histones associate w/ the DNA, chromatin strands condense forming chromatids, and are held together by the centromere until anaphase when they are distributed to each daughter cell

-Replication begins simultaneously on several chromatin threads & continues until all DNA has been replicated

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Anatomy Project

By steveclarke

Anatomy Project. Steve Clarke