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In a tight junction, a series of integral protein molecules in the plasma membranes of adjacent cells fuse together. This forms an impermeable junction around the cell. They help prevent molecules from passing through the extra cellular space between cells that are next to each other.
Desmosomes are anchoring junctions, mechanical couplings scattered like rivets along the sides of abutting cells that prevent their serparation. On the side that is cytoplasmic, is a buttonlike thickening called a plague. Cells next to each other are held together by thin linker protein filaments that extend from the plagues like the teeth if a zipped in the intercellular space. They reduce the chance of tearing. Desmosomes are great for skin and heart muscle.
A gap junction, or nexus, is a communicating junction that allows chemical substances to pass between cells. Adjacent plasma membranes are very close. Cells are connected by connexons. Connexons transmembrane proteins. Gap junctions are found in electrically excitable tissues, like the heart and smooth muscle.
Tight Junctions, Desmosomes and Gap Junctions
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