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DNA Replication/semi-conservative Replcation
***begins simultaneously on several chromatin threads***
1.)DNA helices begin unwinding from nucleosomes
2.) A helicase enzyme untwists the DNA helix and gradually separates the molecule into two complementary nucleotide chains
3.) Each nucleotide strand serves as a template for building a new complementary strand
4.) Machinery needed for replication accumulates in the replisome; RNA primer forms
5.) DNA polymerase III starts at the primer and creates the complementary strands. The leading strand is synthesized continuously while the lagging strand is pieced together
6.) The lagging strand is then put together by DNA ligase. End result is that two DNA molecules were formed from the original DNA helix that are identical to it.
7.) Histones associate with the strands and form two new chromatin strands which are united by the centromere and then condense to form chromatids.
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